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Re: SAM-e and MAOIs » TSA West

Posted by shelliR on April 25, 2002, at 0:23:09

In reply to SAM-e and MAOIs, posted by TSA West on April 22, 2002, at 13:16:26

> Is it safe to combine SAM-e with an irreversible MAOI like isocarboxazid?

It is safe to use Sam-e with a partial or full MAOI. I have Richard Brown's book and tracked down the co-author (Teororo Bottiglieri). He's a pharmacologist who actually wrote his dissertation on sam-e years ago. Anyway, he told me there was no problem with taking nardil with sam-e, and I don't remember his explanation of why it didn't say so in his book.

Anyway, Bottiglieri told me to call Richard Brown; and that he would also put in a call to him. And Dr. Brown called me back and confirmed that MAOIs and SAM-e
were fine together. He ended up speaking with me for almost an hour; going over a protocol for adding sam-e, then talking about other possibilities to add to Nardil if Sam-e didn't work. He was very big on lamictal as an augmentor. He told me to go as high as 1600mg on SAM-E before I gave up. Unfortunately it didn't work for me.


If you're going to try it, "Stop Depression Now" is a good book for information about sam-e, although you can probably get the information from the internet. There was also a bulletin board about sam-e that was helpful, but I don't know after over two years if it's still operating. You might want to do a google search.

Good luck,

Shelli


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URL: http://www.dr-bob.org/babble/20020416/msgs/104072.html