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Re: Buspar and dopamine/tardive dyskinesia

Posted by Flopka on April 19, 2002, at 10:16:04

In reply to Re: Buspar! What is it good for? Flopka, posted by mat on April 19, 2002, at 7:33:46

> hi
> you mentioned that you are concerned about buspars relationship to dopamine receptors.
> i don't know anything about that. does buspirone act like an antipsychotic, or as a dopamine-agonist?

My impression is that nobody really knows for sure what Buspar's deal is with dopamine agonist/antagonist properties. I think believe that Buspar is thought by some to be a potential risk *in theory* for tardive dyskinesia (you know, the horrible type of tremors that never go away, affecting the face, etc). But my impression from what I've read is that in practice, this either (a) has rarely or never been actually reported and/or (b) it's been found that Buspar may actually help control TD-like tremors. I'm not clear on it.

In any case, I don't believe you could even get TD from small doses of Buspar taken over a short period of time. However, I'm always worried about this in the back of my mind. Because I seem to be profoundly in the minority in my positive and QUICK reaction to SMALL doses of Buspar, I am a little paranoid that maybe I am the exception to the rule and will wake up one morning in horrible facial contortions. :-) Since I only plan on taking small doses of Buspar for a limited time (maybe up to 6 weeks), I'm sure there's nothing to worry about. Still, it's in the back of my mind.




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