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Re: SNRIs: Desipramine vs. Reboxetine » SLS

Posted by mat on April 18, 2002, at 6:52:24

In reply to Re: SNRIs: Desipramine vs. Reboxetine, posted by SLS on April 17, 2002, at 21:45:11

hi scott
interestingly, i recently experienced the same worsening of my depression, but while taking another drug that's often prescribed here in austria-milnacipran (a serotonin and noradrenalin ri).
there was no anxiety, but i think i was suicidal for the first time in my life. i discontinued it-and felt MUCH better on the next morning (neither i nor my pdoc could believe that). of course, nobody can predict how one will react to a specific drug, but i nevertheless
do think that the noradrenergic component of milnacipran was at least partially reponsible for my exacerbation. maybe that's a simplicistic view of how antidepressants work, but at least it's a method for me to (try to) understand what could go wrong in my brain (and THAT'S very important for me!)


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URL: http://www.dr-bob.org/babble/20020416/msgs/103409.html