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Re: Does anyone know more?

Posted by djmmm on April 12, 2002, at 11:55:18

In reply to Re: Does anyone know more?, posted by Adam on April 11, 2002, at 22:01:03

I don't think that there is any conspiracy behind the FDA's decision to not approve the Selegiling Patch (for depression) at this time. The facts are, apparently, the outcome of the study shows that it isn't effective, and that the FDA needs additional efficacy info to proceed with this protracted process.

The fact is, (and we all know) Antidepressants often perform no better than placebo...I have never believed that this was due to a lack of efficacy on the part of the antidepressant, but simply due to the power of the placebo effect.

Bodkin's study was promising, this isn't, but this is almost typical of current research. A recent St Johns Wort study using Zoloft and a placebo found that Zoloft was no better than placebo...as we all know, Zoloft has been proven in numerous studies to be effective, and significantly better than placebo.

As far as web info goes...
I know Bodkin is (or was??) on staff at Harvard medical, you can try and search the Harvard site for something..
http://www.hmcnet.harvard.edu/psych/

The Selegiline patch studies were conducted at McLean, here is that site... http://www.mclean.harvard.edu/index.html

I don't know if you will find anything, but it's worth a shot.


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URL: http://www.dr-bob.org/babble/20020408/msgs/102869.html