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Re: buprenorphine stuff » Cisco

Posted by Elizabeth on April 7, 2002, at 21:17:59

In reply to Re: buprenorphine stuff » Elizabeth, posted by Cisco on April 5, 2002, at 16:19:30

> When I asked, not long ago, what was the effect of Buprenorphine's potent 'Kappa Antagonism', you responed with "Absence of effect at the Kappa Receptor".

Did I? That wasn't accurate. I should have said that not only does it lack kappa-opioid effects, it also blocks the effects of other kappa opioids (including endogenous ones).

> > Dare I ask who wrote this?
>
> Dare you may: I'll go back and find the Author. Probably some Wack-O Hack-O-Matic.

<g>

> If you were aware of this, why then the terse reply to my earlier question??

I obviously wasn't thinking clearly. :-}

> Buprenorphine and Effexor combined: Could it be the cutting edge treatment for TRD?

*shrug* I think that for me, several of the standard ADs would have been fine with buprenorphine -- Parnate and desipramine worked as well as Effexor, but Effexor has fewer side effects. I don't know if anyone who's truly treatment-resistant would find this an especially magical combination, though.

What do you think?

-elizabeth


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poster:Elizabeth thread:101178
URL: http://www.dr-bob.org/babble/20020402/msgs/102318.html