Posted by Dr. Kramer on April 2, 2002, at 12:03:54
In reply to Kramer: reason the MAOI patch was rejected?, posted by OldSchool on April 2, 2002, at 0:54:55
> It was recently announced that the much hyped "MAOI Patch" that uses selegiline was rejected by the FDA. In fact this was announced this past week. I feel this MAOI patch is a good idea as there are many TRDepressives who could greatly benefit from an MAOI. But are intimidated by the MAOI diet and the ever present risk of an MAOI hypertensive crisis. The patch is supposed to get rid of a lot of these sorts of problems, eliminate the MAOI diet basically.
> Frankly, I am disgusted this novel drug was rejected by the FDA.
> Do you have any specific knowledge of the reason(s) why this MAOI patch was not FDA approved?
> Old School
Yeah. Unfortunately, it didn't work all that well. A Phase III clinical trial completed a while ago showed no signifigant difference from placebo.