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Dr Kramer: AED cocktails for BPII/NOS.

Posted by JahL on April 1, 2002, at 22:23:23

Dear Dr Kramer.

Another very treatment resistant individual with BP NOS, social phobia, derealisation. Tried in excess of 40 meds.

Another noted pdoc who sometimes frequents these pages suggested I exploit the synergy I enjoy from Lamictal & Klonopin (neither works alone; together they help moderately) and explore complex AED cocktails. ADs are a no-no; tried 15 or so & all worsened my depression (when they weren't briefly inducing euthymia).

Anecdotally, are there any AEDs (I've already added Keppra & Neurontin to no effect) that might be good candidates to add to Lamictal? Oxycarbamazepine? Tiagabine? Topiramate? Zonisamide???

I have read encouraging reports about Lamictal + VPA (which reduced SI when I took it alone) but I am concerned about the obvious interaction.

Do you have any thoughts?

Thanks for your time.





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