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Re: Off Ad's in prep for Nardil: Help? » JohnX2

Posted by Tye on March 31, 2002, at 8:32:12

In reply to Re: Off Ad's in prep for Nardil: Help? » Tye, posted by JohnX2 on March 30, 2002, at 23:30:02

> Tye,
>
> I would like to try parnate, as it sounds like a good party drug (just kidding). I have bpII with some ADD like symptoms and off/on mild atypical depressive symptoms. But the ADs like Wellbutrin and stimulants like Adderall make me manic, hook-line-and-sinker. So I really don't have a full grip on some of my symptoms, although I am not depressed. Do you really feel I could give Parnate a run and not have it drive me manic?

Probably not. I believe parnate and wellbutrin have similar switch rates, lower that most antidepressants. If you have switched on wellbutrin and stimulants, you probably will with parnate as well. Although, one can never predict! If you have good monitoring with your doctors, maybe it is worth a try.

> Currently Serzone, Lamictal, Topamax, and Klonopin are inducing hypomania. But I can't drop the Serzone. The Serzone's AD action is mild enough to be tolerated (unlike Wellbutrin or Adderall).
>
> Could you please direct me to any information on the likelihood of MAOIs inducing mania?
>

I have forgotten where I got that info, let me try a dig it up. Some stuff is in my textbooks, not on line. Well, here is one:

"The Psychopharmacology Sourcebook" by Mark Zetin M.D. page 247 "It appears that cycling from depression into a manic episode is less frequent with wellbutrin, paxil and parnate than it is for the tricyclic antidepressant drugs."

Hope this helped.

Tye


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