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Re: Seroquel gave me bad EPSPsydoc

Posted by OldSchool on March 12, 2002, at 13:01:17

In reply to Re: Seroquel - is it really this dangerous? » Peace, posted by Psydoc on March 9, 2002, at 6:26:44

> Hi . . .
>
> While Seroquel , like any other antipsychotic medication, is capable of causing neurological side-effects, it is clear that such side-effects are quite rare with this medciation.
>
> I have treated many patients with up to 800 mg per day of Seroquel for over a year and have seen no such side-effects as yet. With doses under 100 mg per day such side effects are even less likely to be experienced.
>
> Best regards . . .
>
> Ivan Goldberg
> psydoc@psycom.net
> %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

Doctor Goldberg, I highly respect your psychopharmacology knowledge. There was a time in my depression, when I was totally medication resistant (ADs just totally pooped out) where I found reading your "Depression Central" website gave me hope. Reading the stuff on there helped pump up my morale just a little bit and helped me in the sense that I knew there was stuff out there for me to try.

However, I dont agree that Seroquel is extremely safe. I developed bad EPS after being on low dose Seroquel (50 mg combined with 50 mg Zoloft) for just a one month period. Specifically, 50 mg Seroquel caused the following in me:

1) numb tongue
2) tight, stiff muscles everywhere
3) small muscle "pops" or twitches
4) tightness feeling on the back of my head and in my throat.

After I went off the low dose Seroquel I experienced "rebound" muscle tightness symptoms and the muscle twitches dramatically worsened, and I began having mild weakness on my right side. My psychiatrist confirmed this by giving me muscle tests...my right arm was stiff and rachety feeling when he moved it, while my left arm was loose as a goose. In the following months afterward, the symptoms stayed and have not totally gone away. Ive even had mild problems walking on and off (stiffness in walking) and my right hand and grip feels weaker than before.

OTC benadryl helps this Seroquel induced EPS, and I tried Amantadine briefly a while back and found the Amantadine GREATLY helped these EPS symptoms.

My Seroquel induced EPS dx is official, coming from both my psychiatrist and my family doctor. I did not "self diagnose" this EPS. 50 mg of Seroquel is a piddly dosage.

Old School



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