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Re: Neurontin equals klonopin? » Jill K.

Posted by Ritch on March 3, 2002, at 14:38:46

In reply to Neurontin equals klonopin?, posted by Jill K. on March 3, 2002, at 2:23:30

> My pdoc started my on neurontin for generalized anxiety. I had use klonopin in the past, but developed depression after prolonged use. I am afraid neurontin will do the same.
>
> Don't they both increase the GABA?
>
> I just don't want to feel depressed again like on klonopin. Any advice would be appreciated.
>
> Jill


Jill,

Neurontin has been the best mood stabilizer for my bipolar depression. Neurontin (based on the latest I heard) selectively blocks voltage sensitive calcium ion channels in the hippocampus. The GABA "thing" may not have much to do with how it works on anxiety. I think it would be worth a try. Watch out about the dose, however. Some people can take a ton of it and not seem to get very fatigued or tired, but I couldn't handle more than 300mg 3x daily. Even starting off with that hit me like a ton of bricks. I also take Klonopin with it, and I have to limit my Klonopin dose because it will make me tired and "sullen" (aka depressed), if I take much during the day-esp. if I don't really need to.

good luck,
Mitch


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