Posted by 3 Beer Effect on February 16, 2002, at 2:33:22
In reply to Canadian delema + Adrafinil, posted by Michael D on February 15, 2002, at 16:24:07
> Michael D----I looked around on some of the Canadian pharmacy websites & found that Provigil (Modafinil) is called Alertec. I think Alertec only comes in 100 mg pills & you probably will need the normal (recommended) dose of 200 mg each morning which would cost you $108 US/month.
Personally, I wouldn't order Adrafinil for two reasons-
1. There is no reason to order Adrafinil from questionable quasi-legal overseas pharmacies anymore now that you can order Provigil (Alertec) from Canada.
2. I've read that Adrafinil has a problematic tendency to elevate liver enzymes, & because of this liver toxicity, even if Adrafinil were a patentable & potentially profitable drug it would never pass FDA approval. Even if Adrafinil were approved in the US it would end up with an instant bad reputation-deserved or not- just like (Cylert) Pemoline, the ADD/psychostimulant drug that resulted in 6 cases of liver toxicity after it was release & now is virtually never prescribed.
Provigil was specifically designed to avoid elevating liver enzymes, & passed the FDA approval liver toxicity test. Also Provigil is arguably (& was designed to be) stronger & more effective for narcolepsy/wakefulness & can be used for long term therapy while adrafinil is supposed to be stopped once in awhile (probably b/c of the liver toxicity risk).I would tell you the name of the pharmacy that sells Alertec but that is prohibited on this website, so I would suggest that you look around at all the canadian pharmacies on the internet.
I personally, don't have to order Provigil through the mail since i got a US prescription 200 mg/morning for it & luckily my insurance (Cigna) covered it...
Provigil has been well recieved by most people on this site, but for me the results so far have been relatively dissapointing. It seems to have effects on me similar to a slightly stronger version of sustained release caffeine that lasts 8-10 hours but without caffeine nervousness, anxiety, & insomnia. Seems to noticeably weaker for brain stimulation than the other ADD psychostimulants (but, on a positive note, has less side effects). Once you take the prohibitively high cost into account, Provigil seems to be an overated drug that some doctors are excited about because unlike the other ADD psychostimulants (Sch II), it poses almost no abuse potential (Sch IV). (One amusing study I read was that monkeys preferred & self administered l-ephedrine (OTC Bronkaid asthma tablets) over Provigil!
I think on my next Psychiatrist visit I will ask about switching to Dexedrine Spansules which are like Provigil in that they have a long duration (10 hours?), smooth action, & once-a-day morning dosing. [I tried Dexedrine 5 mg bid before & at that low dose Dexedrine increases talkativeness & self-confidence while reducing timidity. So I am thinking that when combined with high-dose Klonopin, Dexedrine spansules may prove the ideal social phobia combination].
In my opinion Provigil pales in comparison to (Dexedrine, Dexedrine Spansules, Dextrostat, Adderall, Ritalin & Focalin) which I think are far superior & much cheaper psychostimulants/general stimulants.
3 Beers.
poster:3 Beer Effect
thread:94293
URL: http://www.dr-bob.org/babble/20020215/msgs/94373.html