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Re: Lamictal + Dex

Posted by Hattree on February 14, 2002, at 8:48:59

In reply to Re: Lamictal + Dex, posted by Bekka H. on February 13, 2002, at 18:35:15

Ditto on the Spansules--not impressed.

> > Hi Hattree,
> > I know we've had this conversation before, about stimulants. But Dexedrine is the ONE stimulant I haven't tried. Is there any reason for me to believe I may be able to tolerate that one better than the others?
> >
> > Thanks in advance! Hope you are doing well,
> > -cindy
> >
> *************************************************
>
> Hi CindyLou. I'm not Hattree, but I'll try to answer your question until Hattree logs on. For me, Dexedrine has been the best of all the stimulants. It doesn't feel as harsh on my body. As you probably know, Dexedrine (dextroamphetamine) is the D isomer of amphetamine, and supposedly it has more CNS (central nervous system) effects and fewer cardiovascular system effects than Adderall. Adderall is a mixture of amphetamine salts, and only 25% of Adderall is dextroamphetamine. Adderall also has the L isomer of amphetamine and some other salts mixed in. Some people respond better to the mixture; I respond better to just the plain old dexedrine. I read in Stephen Stahl's "Essential Psychopharmacology" that the L isomer, which is in Adderall, has more of an effect on norepinephrine, and the d isomer has more of an effect on dopamine, but both isomers affect both neurotransmitters to some degree. It's probably best to try it and see if it's right for you. By the way, I've also found that the proprietary brand of Dexedrine is much better for me than the generic brand. It seems to last longer and I have less rebound (I'm referring to the immediate release Dexedrine tablets). I haven't had as much luck with the Dex. Spansules (time release), but I know some people who swear by them.
>
> Thank you for your advice regarding the Lamictal. I'm very conflicted about it. I don't know what I'll do yet.


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