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Ben: Moclobemide, TCAs, Anticonvulsants,SSRIs » ben

Posted by TSA West on January 24, 2002, at 3:11:36

In reply to Re: Levodopa as an augmentation strategy ?!, posted by ben on January 24, 2002, at 2:45:25

How long have you been on the Moclobemide? What dose of Moclobemide do you take? If you have been on it for more than 4 weeks at 600 mg or more and still have the drowsiness then switch to something else.

Assuming moclobemide does not work for you:

Seropram and Paxil are in the same medication family (SSRI). Since both of those did not work well for you, you should move to a different family of medications. Secondary tricyclics such as desipramine or nortriptyline would be nice, considering their price is cheap and they have few side-effects. Anti-epileptics with antidepressant properties may be useful, such as Lamictal (lamotrigine) or Neurontin (gabapentin).
Another idea would be to switch to high-dose BuSpar (buspirone). All of these medications will help you sleep and are proven effective in depression.

Every antidepressant takes 4 weeks to work--even Moclobemide. Moclobemide's washout period is rather short, perhaps 2 weeks, so you may start a new medication shortly.

Best wishes to you and your family,
TSA West


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