Posted by ben on January 8, 2002, at 12:27:44
In reply to Moclo » DINGBAT, posted by CalvaryHill on January 7, 2002, at 18:50:37
Moclobemide (Manerix/Aurorix) shouldnt be taken with Venlafaxine (Efexor) because of a rare (but possible !) serotonine syndrom. Discuss this very carefully with you doc. I know one who took Efexor 450 mg with 20 mg Prozac a day and this combo is theortically contraindicated. It depends on your metabolism (liver: CYP450, brain: MAO) how much this to drugs interact.
> The RIMA moclobemide is a "super" antidepressant because it affects serotonin, norepinephrine, and dopamine. And its side-effect profile is benign--even in high doses such as 1000 mg. Its definitely worth a try. Your doctor will tell you whether or not you can take moclobemide with Effexor...
> Have a good day...