Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Remeron- 60 mg, -overly sedating like 45 mg????

Posted by geno on December 17, 2001, at 20:13:10

In reply to Re: Remeron- 60 mg, -overly sedating like 45 mg????, posted by Bill L on December 17, 2001, at 9:09:20

> That might be a good idea to go up to 60mg. It should cause less drowsiness at that dose. But if you still do not do well at 60, maybe you should go back to SSRI's. You said that SSRI's worked better against your depression, but that you had insomnia. I think you should consider taking Ambien along with the SSRI's. It's a very good sleeping medication. Or, Trazodone can also be added to SSRI's to help with sleep. It's also very good.
> > I took Remeron 45 mg for a little over a month and although it sounds like the perfect antidepressant on paper- especially for a social phobic/anxiety prone individual like myself, I had one major problem with it.
> >
> > Remeron 45 mg was so sedating that I was sleeping about 17 hours per day and could not wake up in the morning to do homework or even attend my college classes! It also, compared to the SSRIs (which I can't tolerate due to the insomnia they cause) had little anti-depressant efficacy- I wouldn't even bother to get out of bed to take a shower or shave anymore which is very unlike me- i'm usually a pretty hygenic person when not depressed.
> >
> > I read that in Europe they use higher doses of Remeron and hence have less problems with over sedation. I read in a psychopharmacology textbook that somewhere between 30 & 45 mg of Remeron the increased norepinephrine effects will counteract the strong antihistamine drowsiness effect of Remeron so then it should act like a normal antidepressant without all of the side effects of an SSRI.
> >
> > Obviously for me, this increased norepinephrine effect didn't happen at 45 mg, but has anyone out there been on 60 mg or higher of Remeron? If I sleep 12 hours a night that would be fine with me, but 17 hours on 45 mg is downright ridiculous.
> >
> > 3 beer effect, 23 yr old male.

3 beers,
Last night i upped my dosage to 45mg. I felt a difference. I did not feel as drowsy but still was able to fall asleep. I woke up around 4-5 hours later a bit anxious. I feel this is due to the norepinephrine reuptake. I actually felt a bit "turned on" due to the alpha 2 blockade. I had to take an ambien to fall back asleep. i then woke up 4 hours later. So total i got 8 hrs of pretty decent sleep. Then in the am, i took .5mg of xanax, which helped my anxiety during the day. I DID feel more stimulated at 45mg during the day, esp some libido!! Remeron at 30mg is more sedating, lowering my libido. At 15mg, is basically a sleeping pill.

I got this from prescorn. com

15mg- basically blocks histamine
30mg, histamine and 5ht2a blockade
45mg higher- norpepinephrine

most p docts start you out at 30 mg which is in the middle. If extreme insomnia and anxiety are your problem, like me, id stay at 30mg. if i felt too blau and sedated, id up it to 45mg. At 15mg, id more likely take an ssri with it to improve seratonin reuptake, using 15mg as a sleeping aid >

any comment would be helpful.

at 45mg, again tonight, im adding ambien 10mg if i wake up. Then xanax to combat any anxiety next day. No too sedated nor too stimulated at this combo.





Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:geno thread:87108