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Re: sublingual buprenorphine tabs (Subutex, Temgesic)

Posted by Annie Z. on December 17, 2001, at 11:44:25

In reply to sublingual buprenorphine tabs (Subutex, Temgesic), posted by Elizabeth on December 15, 2001, at 9:51:25

Sorry, I canít answer any of your questions for you. If you donít mind, I do have some questions for you though regarding buprenorphine administration. I am trying to find out is which way of administering bupe would give me the best results.

What method of administration did they use at McLean where the study or studies produced some extraordinary results for some people? One of the articles of the McLean Hospital studies says that they used the sublingual route of administration. Did they use the liquid or tablet form of the drug sublingually? Instead of administering the liquid form of bupe (which is the only form currently available in the U.S.), perhaps the hospital got sublingual tablets from Europe; or had a lab convert the liquid into the pill form. Anyone know?

How effective is the sublingual pill, which is currently available in Europe? Do you, Elizabeth, or anyone from Europe know?

As far as taking bupe sublingually, I believe that you (Elizabeth) said that taking the liquid medication sublingually is an ineffective way to take this medication because you tend to swallow some of it, and thus do not get the benefit of the full dose.

In another one of your posts, Elizabeth, you said taking bupe intranasally is difficult because of the strange procedure of taking the medication out of the vial with a syringe, and then breathing it up your nose. I would think for privacy reasons, you would probably need to find a restroom four times per day to administer this medication Ė very inconvenient.

Perhaps bupe could be administered as a shot? This probably wouldnít be better than taking it intranasally, since you definitely would need some privacy to administer it this way.
Anyone have any comments on the above paragraphs or about buprenorphine administration in general?

Also, several last questions, Elizabeth. How are you doing on your current dose of buprenorphine? How much medication do you take? Canít you take more of it to increase its effectiveness? What have you heard about the sublingual tablet of buprenorphine coming out? When are these tablet coming out?

Finally, I am very interested in buprenorphine. I've read all of the several medical articles on bupe and depression, I've done searches on usenet and the internet, etc. Once,I even did a search +Elizabeth +buprenorphine on all the different time periods on this site. So I would be interested in the e-mail dialogue that you may have with Cisco. Could you either publish it on this bulletin board or send me a copy at

Thank you in advance to anyone who can give me more information on buprenorphine administration.




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poster:Annie Z. thread:86976