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Re: dopamine receptor supersensitivy » SLS

Posted by JohnX2 on November 4, 2001, at 13:49:24

In reply to Re: dopamine receptor supersensitivy » JohnX2, posted by SLS on November 4, 2001, at 12:28:16


Thanks Scott,

I have come across Ibogaine references.
It is definately interesting.

Any luck with your treatment path?
Are you steady with your current
meds?

-john


> Hi John (and others)
>
> > Looking for info on dopamine receptor
> > supersensitivy articles/background.
> > Experts out there?
>
> Not me.
>
> > Have read interesting theories on how
> > psychostimulants can cause dysfunctional
> > pre/post synaptic dopamine receptor ratios,
> > sensitivity,feeback inhibition.
> > I also believe this could be a source of med-poop out.
> > Also believe that it can be reversed
> > (possibly using an NMDA antagonist
> > + a dopamine agonist/antagonist). Just a hunch...
> >
> > -john
>
>
> Check-out ibogaine:
>
> http://www.med.nyu.edu/Psych/ibogaineconf/objectives.html
>
> It is a NMDA receptor antagonist that has quite a bit of history involving use for the treatment of drug addiction. It seems to prevent or reverse neuroadaptive changes (eg. receptor sensitivity) resulting from drug exposure. It also does a bunch of other things that I'm sure you'll have fun researching.
>
>
> - Scott


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poster:JohnX2 thread:82845
URL: http://www.dr-bob.org/babble/20011104/msgs/83179.html