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Re: opiates and major depression

Posted by Elizabeth on October 19, 2001, at 12:44:17

In reply to Re: opiates and major depression, posted by JohnL on October 18, 2001, at 2:27:48

> ... I went and did some research on Ultram. As it turns out, it is a lot more than just an opiate. It apparently is similar to Effexor, in that it inhibits the reuptake of serotonin and norepinephrine.

Ultram isn't really much of a monoamine reuptake inhibitor at safe/accepted doses. It's basically just a weak opioid that has been plugged as something "different." (Don't tell the FDA.)

> There were a surprising number of cases of serotonin syndrome when patients combined antidepressants with Ultram.

Also true of Demerol.

> I saw one study where a patient with refractory major depression was treated successfully with Ultram monotherapy.

It can also help with OCD and social phobia.

> Simply tell a potential doctor that you are experiencing success with Ultram and that all you need is someone who will provide maintenance prescriptions and monitoring of progress.

Frankly, I think it'd be better to say that you had Ultram for pain once and it really helped improve your mood, and leave out the part about self-medicating (which would most likely get you labelled an "abuser").





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