Posted by paxvox on October 18, 2001, at 16:26:21
In reply to opiates and major depression, posted by androog on October 16, 2001, at 16:49:58
Ultram is not an opiate, actually. It does show affinity, and does bind with opiate receptors. It behaves very much like an opioid, even to the extent of cravings and physical and psychological dependence. I guess it is similar to meds like Wellbutrin, that while not true stimulants like the amphetamines, present with very similar characteristics. Ultram is not an FDA controlled substance.
NOW, to try to answer your question. Yes, I believe some people respond paradoxically to the sedative effects of opiates and their cousins. Personally, I have this type of reaction. The long-term use of opiates as AD med treatment would probably not be found in too many mainline docs. However, some docs will try certain meds if nothing else helps. I would think, however, that chronic opiate use would quickly lead to tolerance, and addiction that ultimately would kill you (or make you wish you were dead). Perhaps this is why heroin is so popular? I clearly have not given you a very scientifically sound answer, but a subjective one. Take from it what you will.