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Levonorgestrel IUD (LNG-20) and depression

Posted by AnneL on October 5, 2001, at 23:37:22

I have been diagnosed with Major Depression and have been on Effexor XR with pretty good results. I also have been diagnosed with adenomyosis and in the hopes of avoiding a hysterectomy at age 41, my GYN suggested I try the now available "Mirena" IUD which releases approximately 20 mcg. of the hormone Levonorgestrel daily.

My mood has markedly been more depressed since the IUD was placed, but I am reluctant to give it up because it has stopped the excessive bleeding. Is there anything I can do to counteract the effects of the progestin Levonorgestrel which I understand is a fairly androgenic synthetic hormone? The blood levels are supposedly very, very small in comparison with those found in combination Pills. I am on Effexor XR
225 mg. which was helping considerably. I am now back in the dumps so to speak. I would appreciate anyone's thoughts on the subject. I really don't want to have surgery at my age. Thanks Anne




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