Posted by Cruz on September 10, 2001, at 7:20:41
In reply to Cruz: Ketoconazole, posted by Cecilia on September 10, 2001, at 4:53:26
I'm in the US. I have'nt noticed any side effects. The brand I'm using is Nizoral made by Janssen. I took one 200 mg tablet about 6 days ago. My improvement was immediate. Its has stayed that way so far. I am keeping my sleeping hours consistent. So far so good. I had been takeing amisulpride and DHEA for a months or so, but may discontinue these. They were'nt helping very much until I took the Nizoral.
> > So far Nizoral(ketoconazole) is working great!
> > I'm experimenting now to see how small a dose I can get by on. Anybody on anything would be prudent to not take any more med than is needed. That goes for anything we ingest, food,water,etc..
> > We crave to understand how things work. How any of these meds work is not entirely known. Is the good response to Nizoral because it lowers cortisol or because it directly affects my circadian rythmn itself or is it doing something else. At this point, of our understanding of mood disorders there is no answer. Good luck!
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> > > Do you have any links on the use of ketoconazole for depression? I understand that even though it`s an antifungal drug it`s used experimentally in depression to lower cortisol levels but I believe it`s a pretty toxic drug. Also since depression and stress increase cortisol levels how do you know which came first? You mentioned having abnormal circadian rhythms and I definitely have that. As long as I can remember I`ve woken up totally exhausted and in almost physical pain from overwhelming depression, no matter how much sleep I`ve gotten, then when I try to go to sleep at night I have severe insomnia (Fortunately I work an evening job as it takes every ounce of will I have to drag myself out of bed at noon.) Is this the type of circadian rhythm problem you have and did the Ketoconazole help it? Also I read somewhere that Tianeptine lowers Cortisol levels, have you tried this?
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> I don`t know where you`re posting from, but if it`s the U.S. or Canada, your circadian rhythms must be similar to mine! What kind of side effects have you had with Ketoconazole? Cecilia
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poster:Cruz
thread:78445
URL: http://www.dr-bob.org/babble/20010907/msgs/78453.html