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Re: Great Combo for TRD. Adamie

Posted by JohnL on August 19, 2001, at 17:36:32

In reply to Re: Great Combo for TRD. Prozac + Zyprexa + Adrafinil » JohnL, posted by adamie on August 19, 2001, at 11:43:10

>
> hi john. I just had an idea. To see if prozac doesn't effect me negatively like two seratonin meds have I will try to get a free sample tomorrow. Because tomorrow I will be seeing my pdoc. We were going to add something to the 5mg zyprexa I am taking. I will probably choose wellbutrin or reboxetine (supossed to be good for depression with extremely poor thinking ability). But as I pick one of these I will also ask the pdoc if I can get some prozac free samples first. With the effexor I felt during the second day how horribly it was affecting me. Therefor I should see how prozac will effect me within a few days also. if it doesn't make me worse then perhaps it could work very well for me. so I will see.

Hi Adamie,
I like your idea. Here's the trick though. You will likely get either 10mg or 20mg capsules. It's just my opinion, but that is way too much to start with. You could indeed feel things you don't want to feel if you start right off with one of those doses. So here's what you can do. It worked great for me. I too was very sensitive to SSRIs, and like you many of them actually made me feel worse. Here's the trick...

Take the capsule, open it, and dump the contents into a glass of orange juice. The Prozac will not dissolve, so stir it well to be sured it's mixed up well. Then drink a custom size dose, a SMALL custom size dose. For example, if it's a 20mg capsule, drink just 1/8th of the glass. Just a sip to start with. Save the rest in the fridge for the next time. Then the next day, stir it well again and drink another 1/8th. After a couple days, you can increase it to 1/4 glass. Eventually you could do 1/4 glass twice a day instead of just once. Just keep going at this pattern until you reach 20mg a day. For me that took about 3 weeks.

I say go for it! Just do the juice trick and keep it real low at first.

By the way, you mentioned Reboxetine. You know, I can't think of a single person yet who has tried it and liked it. For me it was horrible. Not to mention the total impotence it caused. But for the kind of symptoms you have described, you could well have a deficiency in the norepinephrine circuitry. I think Reboxetine is the wrong way to go about fixing that chemistry. A much better bet is Adrafinil. Adrafinil just so happens to work good on the symptoms you have. It's cheap and has hardly any, if any, side effects. And to top it off, it happens to go real well with Zyprexa and/or Prozac.
John


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