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Re: SSRIs vs Appetite Suppressants - bizarre » Joe Schmoe

Posted by MB on August 8, 2001, at 15:57:52

In reply to Re: SSRIs vs Appetite Suppressants - bizarre, posted by Joe Schmoe on August 8, 2001, at 14:25:16

> I am just liking this anti-appetite effect of the Wellbutrin so much that I am starting to get interested in the idea of appetite-suppressing drugs in general, in case the Wellbutrin ever poops out or these chest pains become unbearable (like today). I never really looked into appetite-suppressing drugs before, are there any good ones? I am always surprised to see some sold as over the counter or herbal ones, given that the heavy duty ones always seem to end up controlled substances.


Most of the drugs used for appetite suppression are CNS stimulants (like the psychostimulants used for ADD). I think a long time ago, amphetamines were the main drugs used. Then they tried to synthesize "less addictive" appetite suppressants. I think a couple that came out were Preludin and diethylbupropion (which, by the way is related, structurally, to your Wellbutrin--bupropion), but I think these were still pretty euphoric. I met a guy that used to take Preludin to get high. Most of the uppers that have psychostimulanting effects improve mood, I think. I think there has been a search to find a appetite suppressant that doesn't act as a psychostimulant (ie. with no abuse potential). The medical community wants people to lose weight without feeling good, I guess.

The over-the-counter appetite suppressants are stimulants also, but they are mainly "sympathimimetic" drugs like the decongestants. They work more on the body and less on the mind. So, they're likely to feel like Sudafed or ephedrine (decongestants in cold medicine). PPA was a big over-the-counter appetite suppressant until they found out it gave people stokes (it constricted blood vessles, which is why it makes a good decongestant also: it decreases blood flow to swollen tissue in the nose).

If the appetite suppresant drugs work for you, then maybe it is their psychostimulating properties doing so. Maybe a medication like Ritilin or Dexadrine might help you.


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