Psycho-Babble Medication | about biological treatments | Framed
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Re: jumping in - Shelli, Lorriane,

Posted by Elizabeth on August 4, 2001, at 15:33:57

In reply to Re: jumping in Elizabeth, Lorriane,, posted by shelliR on August 3, 2001, at 18:28:03

> It's interesting, my sister just told me recently that my SIL thinks that I don't try hard enough to overcome my depression. This is actually fascinating to me.

"Fascinating" is not the word I'd use to describe it!

It sounds like your sister-in-law is a judgmental person in general. A lot of people are like that: they have strong opinions on subjects that they know nothing about.

> Elizabeth, what is would be affected by having too high a blood level. Could it affect your organs? Like liver damage, etc.?

The main risk is cardiotoxicity, actually. The heart has to be working like clockwork, and if it gets out of sync even a little bit, you can get major problems. An ECG would find any such problems, though.

I sort of feel sorry for the poor guy who's covering for my pdoc, having to deal with all this stuff!

I agree with you about ECT: I think that any medication is preferable to it. Even if you developed tolerance and had to keep increasing the dose, I would say that opioids are safer than ECT, except perhaps for people who have addictive tendencies. And even then, with proper monitoring I believe it can be done safely. (The first thing you become tolerant to is the respiratory depression, so increasing the dose to compensate for tolerance is safe -- you can't do this safely with some other types of drugs, such as barbiturates.)

> BTW, in regard to back pain and meds, selegiline gave me back pain, really shoulder pain almost from the start, although I didn't think to associate it with it until I started to get bad pains in my legs. When I went off of it, both the shoulder pain and leg pain went away.

I wonder about this sort of thing; do you think it might be related to the amphetamine metabolites of selegiline? (They're the l- enantiomers, and they have more peripheral and less central effect compared with d-amphetamine and d-methamphetamine (Dexedrine and Desoxyn).)

Buprenorphine does away with my back pain completely, and unlike other things I've tried (Valium, Soma, Ultram), it works reliably. It's also much less expensive than having a facet block every week would be. :-)

> Once I knew I had kids inside, as each one let her presence be known, I was always co-conscious.

Did you have periods of lost time before that?

> So no, "DID in partial remisison" would not work for us.

Damn. :-)

> Today was a pretty good day and I didn't supplement the oxy. And the plan was always to have an AD in there also, because the AD I was stopping was prozac, I had a long waiting period. Monday is five weeks.

Ahh. That's the main down side of Prozac, IMO: the long washout period. I definitely think that opioids are usually best used in combination with antidepressants rather than by themselves; short-acting drugs (such as opioids and stimulants) can be destabilising, and an AD can smooth things out.

> > Desipramine isn't a perfect success, but it does seem to be a suitable substitute for Parnate (with less hassle involved).
> and it gives you more options for adjuncts.

Yes. I'm particularly interested in seeing whether psychostimulants would help me, since Cylert worked in the past and since I have ongoing attention problems.

> Have you ever tried buprenorphine in pill form , sub-what-ever?

Subutex and Temgesic are the brand names that I'm aware of. No, I've never tried getting medication from outside the U.S.





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