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Re: Mixing Wellbutrin and SSRIs: Seizure risk?

Posted by Ted on August 2, 2001, at 11:14:47

In reply to Mixing Wellbutrin and SSRIs: Seizure risk?, posted by Joe Schmoe on August 2, 2001, at 8:15:28


I take Wellbutrin SR 150mg BID with Zoloft (SSRI) 200 mg/day. The seizure risk of wellbutrin is really overstated. Mixing with SSRIs has little risk if monitored while the SSRI dose is increased. The combo of wellbutrin + SSRI is a very good one for treating depression.


> I notice there is a trend to add Wellbutrin to SSRIs to combat sexual side effects. However, when reading the Wellbutrin literature, it says its seizure risk is increased when mixed with other medications which lower the seizure threshold, "such as other antidepressants."
> Is it safe to mix Wellbutrin and SSRIs?
> I am taking Wellbutrin right now but I know someone else who is taking Wellbutrin SR 150/day (low dose) and her doc added Celexa "for the serotonin effects." Not sure what that means in terms of results - what will Celexa deliver that the Wellbutrin will not? But in any case I was wondering if it was safe.




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