Posted by JohnL on July 31, 2001, at 4:33:20
In reply to TREATMENT RESISTANT DEPRESSION - INFO NEEDED, posted by sweetmarie on July 29, 2001, at 4:18:21
Disclaimer, mileage varies. However, in my experience, treatment resistant depression usually means the doc and the patient are barking up the wrong tree. In other words, they are trying drugs in the wrong category.
It's a hit-and-miss game, since we all have unique chemistries, unique problems in those chemistries, unique genes, unique personality and circumstances. Based on what I have seen in others over the years, based on exhaustive research, and based on this board, the highest potential for success in TRD involvs combinations of any of these:
Prozac
Zyprexa
Adrafinil
Amisulpride
Risperdal
Forget everything else until these have been exhausted. My TDR has been successfully treated with 20mg Prozac + 5mg Zyprexa + 300mg Adrafinil. It is worth noting that while these drugs are working miracles for me, they are doing so at the minimum doses. It's just my opinion, but the farther away a drug is from treating the true underlying problem, the higher the dose is required. The closer it is to the real problem, the lower the dose.
John
poster:JohnL
thread:72327
URL: http://www.dr-bob.org/babble/20010731/msgs/72701.html