Posted by chiaratara on June 30, 2001, at 2:14:37
In reply to Serzone + Dopamine Agonist = Serotonin Syndrome?, posted by joema on June 25, 2001, at 14:35:30
I found those to be the side effects of serzone. Flu like symptoms and just feeling "out of it."
I tried serzone for about a month and stopped because it was much too sedating. I started at 50 and then wound my way up to 150. I had similar symptoms when I started on 50mg. I didn't go to work for three days and didn't drive because I would literally space out for seconds and not remember things.
One story, about a week into taking serzone, I was in a parking lot waiting for someone to pull out of a spot, so I could pull in. The next thing I knew, I was parked in a different spot. Serzone made me quite loopy, and the symptoms you are describing are not unusual in my opinion, however, i am not a doctor. Is the same doctor prescribing both drugs? If not, run it past your doctor. If the DR gives it the all clear, I would not doubt that your symptoms have to do with Serzone.
I even had the blurred vision and went to actually thought my vision had changed dramatically in the course of a few days. Tricky stuff.
The started pack I received from my doctor contained gradual dosing, which is probably a big hint that you should start out with a smaller dose and work your way up. The starter kit was from the drug company.
I hope it is helping.> I'm a 43-yr old male with a 4mm prolactin-secreting benign pituitary tumor called a prolactinoma. I take 0.5mg/week of a dopamine agonist med called Dostinex (Cabergoline), which controls my prolactin level and prevents the tumor from growing.
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> I also have mild depression/anxiety, for which I'm trying various ADs. When I took 150mg of serzone, within 2 hrs I had hypomania, diaphoresis, shivering, 102 temp, nausea, blurred vision, marked flu-like symptoms. It gradually abated over 24 hr.
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> Are there known drug interactions between dopamine agonists and Serzone? Did I have serotonin syndrome, or just individual sensitivity to a (maybe too high) starting dose?
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> Can I start at a much lower dose of serzone (say 20 mg), and just very slowly increase? Are there risks to doing this given the above?
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> -- joema
poster:chiaratara
thread:67835
URL: http://www.dr-bob.org/babble/20010625/msgs/68453.html