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Re: Does Effexor poop-out ? NikkiT2

Posted by SLS on May 27, 2001, at 14:34:02

In reply to Re: Does Effexor poop-out ? SLS, posted by NikkiT2 on May 26, 2001, at 18:14:28

Hi Nikki x

Thank you very much for your reply.

> I wasn't on it (well, is till am, but stick with me!!!) it long enough for a poop out, but I did have a one month break from it (including cold turkey withdrawal from hell) and it has never worked well like it did first time.

>:-(

Damn.

If you are still taking Effexor, perhaps you can coax it along with the addition of another drug. There are lots of alternatives - too many for me to guess as to which ones are the best bets - especially without knowing what you have already tried.

Two common and often successful choices to augment Effexor are Wellbutrin and Remeron. Lithium augmentation using low dosages (300mg - 600mg) is sometimes overlooked as is the use of thyroid hormones (something that appears to be more successful in females).

It would be interesting to see how you would respond to the addition of any of the following: (not that you should be my guinea-pig :-) )

1. Pindolol

2. Buspar

3. Geodon

These three drugs manipulate the serotonin 5-HT1a receptor directly in one way or another. SalArmy4Me can comment further on these drugs. Geodon is a drug that belongs to a class of drugs most often used to treat schizophrenia or other psychoses. As such, it must be considered to have the potential to produce some significant side effects resembling movement disorders, even though it is thought to have a much reduced risk of doing so as compared to the older drugs. Although new, Geodon has already demonstrated an ability to produce potent antidepressant responses in some people for whom nothing else has worked.

On paper, and in a simplistic fashion, one can try to hit the same serotonin receptors as does Geodon by adding both Buspar and Serzone together with Effexor.

Hopefully, you won't need to investigate any of these more exotic things, as you may do just fine with the simpler and more common treatments.

If nothing else, knowing that alternatives like this exist should be enough for you to feel optimistic that you will find something that works well.


- Scott

 

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