Psycho-Babble Medication | about biological treatments | Framed
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Re: Cam » ben

Posted by Cam W. on May 26, 2001, at 13:01:03

In reply to Re: Cam, posted by ben on May 26, 2001, at 12:34:39

Ben - Paxil™ (paroxetine) is a bugger (no pun) for sexual disfunction (unless you have a hair-trigger). Also, be aware of the delayed weight gain that is very common with Paxil. Four or five months after starting the drug you realize that none of your clothes fit. I recommend that everyone who start Paxil get some kind of dietary counseling (ie. keep a food diary to make sure that your eating habits don't change and keep a decent exercise program).

As for the Edronex™ (reboxetine), it is not my favorite drug. We had a clinical trial or two with it at our University hospital and, after some seemingly initial success, many of the people who tried it relapsed. I believe that, if ever released in the U.S. and Canada, may find a niche market for those who cannot tolerate or don't respond to SSRIs. The side effects that you had do sound like start-up side effects. Another trial may be in order, but like I said, only a select few respond and maintain response on Edronex.

I am not totally convinced that taking away either norepinephrine- or serotonin-reuptake blocking activity from an antidepressant works as well as an antidepressant that has both activities. It seems that TCAs which affect both of these mechanisms work better than either SSRIs or NRIs. Perhaps blocking both leads to a third action in the brain; one we haven't figured out, yet.

I'm sorry, I can't remember whether you tried Wellbutrin SR™ (bupropion), yet. It would seem a logical choice. You could also add it to Celexa™ (citalopram) to try to reverse the sexual stuff. Ask your doc about this.

- Cam




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