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Re: I'm a little scared of these drugs...

Posted by geekUK on May 20, 2001, at 20:20:59

In reply to I'm a little scared of these drugs..., posted by roo on May 15, 2001, at 11:26:50

The way I understand it the seretonin reuptake inhibitors need time to build up to a decent level as the body doesnt tolerate them well- thus the 2 week+ action time. However (I am sure) the effect comes from the fact that outside the sinapse if the seretonin is not reuptaken into the cell it sits about, triggering the synapse more. Therefore more effect from the release. The thing that I am worryed about is the REALLY underresearched area of the effects of this extracellular seretonin. I know that a lot of research in the area of dopamine+parkinsons has pointed to desensitisation of the receptors with meds. This means the dose must be upped. Maybe (and no one really knows this) the same effect to a large or small effect may happen in SSRI's. So you have every reson to question if this is happening. Dont expect the doctors to agree with you, they dont know either. In many ways we are all guinea pigs for this batch of antideppressants. But one thing I am sure is that the brain is VERY adaptable. So taper the dose as fast as you can, but bear in mind the time you have been on the drug and the amount of time it will take to reverse the effect (if it is this, and howeverlong it takes- remember your the guinea pig!)
Hope you get off them soon with no -'ves. The sex thing is a B***D! HEHE.
M


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poster:geekUK thread:63095
URL: http://www.dr-bob.org/babble/20010515/msgs/63749.html