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Re: Zyprexa, Risperdal fears » Lawrence s.

Posted by SalArmy4me on May 17, 2001, at 2:32:31

In reply to Zyprexa, Risperdal fears, posted by Lawrence s. on May 17, 2001, at 1:26:51

There is no evidence to suggest that atypical antipsychotics lead to psychosis on discontinuation. And they can only help your depression:

O'Connor, Manjula et al. Adding Risperidone to SSRI Improves Chronic Depression. J of Clin Psychopharmacology. 18(1):89-91, Feb 98:
"...These patients had in common: a long course of illness, inadequate response, episodes of major depression, and lack of manic or psychotic symptoms. Risperidone was used for the suicidal ideation and agitation that were present in depression and anxiety. These symptoms, and disturbance in sleep and eating behavior, had responded poorly to an SSRI without risperidone. The improvement with risperidone was fast, and a short-duration of treatment was sufficient to control symptoms in some patients."

Shelton, Richard C. et al. A Novel Augmentation Strategy for Treating Resistant Major Depression. Am J of Psychiatry. 158(1):131-134, Jan 2001:
"The combination of olanzapine with fluoxetine in patients with treatment-resistant, nonpsychotic, unipolar depression produced superior improvements over either agent alone across a variety of measures. Clinical responses were evident by the first week, suggesting rapid onset of action... Overall, treatments were well tolerated..."


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URL: http://www.dr-bob.org/babble/20010515/msgs/63318.html