Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Switching from Risperdal

Posted by JohnL on November 23, 2000, at 6:31:32

In reply to Switching from Risperdal, posted by JEdwin on November 22, 2000, at 21:42:41

You might want to check out the posts titled "Question for Risperdal users" starting on 11/17/2000. Dr Bob gathered some comments from other doctors concerning Risperdal that are very interesting. You may be able to play with Risperdal dose sizes, and may find lower is sometimes better than higher.

I think Zyprexa or Amisulpride could be excellent choices to replace Risperdal. Your doctor can instruct you on how to switch from Risperdal to Zyprexa. Amisulpride is an excellent choice from Europe. Since it is only available from international mailorder pharmacies, and not FDA approved, I'm not sure your doctor would be able to participate. It is however a choice to keep on the back burner. Zyprexa would seem to me to be the very best choice at this time.

Though each doctor probably would handle it differently, I don't see any need for a wash out period. But whether you do a washout, or just stop one and start another, or slowly decrease one while slowly add in another, I think you should expect some weirdness in that transition zone. After two years, no matter how a switch is accomplished it will likely involve some weird feelings during the change. So be on the lookout and be prepared. Hopefully it would go smoother than expected, but still some caution and respect is warranted. Make sure your doctor is easily reachable during a transition.

I am curious. Do you primarily experience the positive symptoms or the negative symptoms of schizophrenia? Or is it a mixture of both? Is one more prominent than the other? There are two sides to schizophrenia, and I think which side you tend to experience the most could have a strong influence on which drugs should be used. For example, if you have primarily negative symptoms, then choices could be: 1)lower dose of Risperdal; 2)addition of Ritalin or Adderall to Risperdal; 3)addition of antidepressant to Risperdal; 4)Zyprexa; 5)low dose Amisulpride; 6)low dose Sulpiride. If you have primarily positive symptoms, then choices would more likely be something like: 1)increased dose of Risperdal, with another drug added to remedy the akathesia (if your doctor doesn't know what drugs do that, then yeah you probably need a new doctor); 2)Zyprexa; 3)mid-high dose Amisulpride; 4)mid-high dose Sulpiride.

What's better, optimizing Risperdal or switching completely to Zyprexa? I generally think optimizing an existing drug is best. But in your case it might be better to think about trying Zyprexa for a month or so and see how it goes. All evidence suggests it could be a superior replacement. But in a worst case scenario, you could always return to Risperdal and begin optimizing techniques. Though I could see-saw back and forth considering the pros and cons of your alternatives, Zyprexa just seems to stand out as the best choice at this time. It's primary drawback might be a bit more sedation and weight gain than Risperdal.

Hope something here is helpful.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:JohnL thread:49274