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Re:More on Viloxazine. Betamimetic AD? Scott

Posted by Anna P. on November 8, 2000, at 21:40:50

In reply to Re:ATTENTION ANERGIC DEPRESSION SUFFERERS, posted by SLS on November 7, 2000, at 21:28:18

> Hi again.

I found more info on Viloxazine. I'm concerned, and I dropped Reboxetine from my combo today after having heavily increased heart rate.
According to my research , I know that Viloxazine is contradicted with Carbamazepine, as it increases its blood level.
How about Neurontin?
I need to take Neurontin as it makes ADs to work to some extent.
Viloxazine works with Neurontin for now.
But I've found out that a drug has the anticonvulsant and proconvulsant properties.

1.Psychopharmacology (Berl) 1982;76(3):212-7
Anticonvulsant and proconvulsant properties of Viloxazine hydrochloride: pharmacological and pharmacokinetic studies in rodents and the epileptic baboon.

2.Neuropsychobiology 1987:17(1-2):35-40
Viloxazine as a betamimetic antidepressant drug

A comparison was made between the effects of maprotiline, the sole action of which is to inhibit the reuptake of noradrenaline, of salbutamol and of viloxazine on hypothermia induced by reserpine, oxotremorine or apomorphine. The dose/effect curves in the three tests showed a similarity in profile between viloxazine and salbutamol, whereas no resemblance was evident between these two drugs and maprotiline. These facts suggest that viloxazine which has a weak effect on noradrenaline reuptake acts probably as antidepressant by betamimetic activity.

Scott, what does betamimetic activity means?

Anna P.


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poster:Anna P. thread:48258
URL: http://www.dr-bob.org/babble/20001102/msgs/48478.html