Posted by Anna P. on November 7, 2000, at 14:21:43
In reply to Need Some Drug Advice, posted by JohnL on November 7, 2000, at 4:27:33
>
Could you try Sulpiride? For me it worked without
the sexual side effects.Anna P.
I need some help from my drug expert buddies out there.
>
> As everyone knows, I've done extremely well with low doses of Amisulpride+Adrafinil. I have one and only one side effect. But it's a bad one. Impotence.
>
> My pdoc retired. My GP moved away. Out in the cold, I had to find a new doc. I found one. I spent no time researching, I just sought the GP nearest to where I live. As it turns out, I got lucky, he's awesome. We discussed everything in detail, but still I need feedback from folks here at this board.
>
> His first suggestion was to try Viagra. I didn't like Viagra, but may have to revisit that option if all else fails.
>
> His second suggestion was to try me on one week of extended release Ritalin instead of Adrafinil, and then one week of Adderall. I couldn't believe it! Has this guy been reading Jensen stuff, or what?
>
> If these trials don't turn out well for whatever reason, then next he would have me restart the Adrafinil, and possibly try an alpha-1 antagonist to counteract it on an as-needed basis. I think he mentioned Prazosin. This maybe in combination with Viagra.
>
> In the end, if all these things fail, then he would have me consider longterm trial of Wellbutrin in addition to my other drugs.
>
> My question to you all is this...Do you think an alpha-1 antagonist like Prazosin could counteract the agonist activity of Adrafinil? I read one clinical study where Prazosin did do that to Provigil. But I also wonder if that is something that could happen right away, or whether it is something that would take time. I mean, Adrafinil takes time to work. From what I've read about Prazosin, it takes time too. I wonder if it would have any effect on an as-needed basis.
>
> I also noticed there is a drug called Nicergoline that is also an alpha-1 antagonist which is supposedly much more competitively powerful in site binding than Prazosin.
>
> Anyway, I was surprised to find a doc who had no problem with my current meds, and who is willing to tweek out the details. A soft lifeless genital organ is my concern. He says this soft relaxed muscle condition is common with any alpha or beta agonist. I would welcome any and all feedback from anyone.
> Thank you,
> John
poster:Anna P.
thread:48342
URL: http://www.dr-bob.org/babble/20001102/msgs/48378.html