Posted by Leonardo on October 27, 2000, at 11:45:25
In reply to Reboxetine onset of efficacy Q more....., posted by JahL on October 26, 2000, at 13:10:50
I have taken reboxetine for more than a year in different combos with Paxil and mirtazapine (in the UK).
Be aware that I had some bad side effects when starting up reboxetine too quickly, ie after the fisrt 4mg pill! Problems include intense irritability and violent outburts. I would recommend starting at 2mg for the first day and working up gradually. I've never taken more than 8mg per day, 4 or 6 usually does the trick for me, taken with paxil. The stimulation effect does wear off after a while though.
Also unless you want insomnia, take your doses in the morning and at lunch time, not later.
> Could anyone with any experience of Reboxetine please give me an idea of how its speed of onset of relief compares with that of other antidepressants (I have tried them all)? Is it the standard 2-3 week wait? I intend to start high & fast and progress to 12mg/day as soon as.
>
> Also, I am currently 1 & 4 weeks into trials of Serzone & Adrafinil respectively. Neither has yet yielded any positive results but in the abscence of any real side effects, I am tempted to keep both on (esp. the Adrafinil) in the hope of a fortuitous interaction with Reboxetine.
>
> I know polypharmacology can be a risky business, especially without the direction of a pdoc, but my need for relief (of dysthymia+social phobia+double depression) is so urgent that I am prepared to trade the risks posed by a shotgun/scattershot approach for a statistically greater chance of success. I am even considering throwing Provigil into the pot.
>
> No pdoc here in the U.K. will prescribe me stimulants (which supposedly offer fast-acting relief)
>
> Any thoughts? Anyone?
>
> Thanx in advance,
> ta,
> Jah.
poster:Leonardo
thread:47408
URL: http://www.dr-bob.org/babble/20001022/msgs/47513.html