Psycho-Babble Medication | about biological treatments | Framed
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Re: AndrewB, S.D., and JohnL

Posted by JohnL on September 9, 2000, at 5:30:43

In reply to Re: AndrewB, S.D., and JohnL, posted by AndrewB on September 7, 2000, at 18:46:27

Bill,
You ask tough questions! :-) I'm not sure exactly how I would trial these meds. There are so many options.

You could add in the Amisulpride along with everything else you are already taking. I would prefer not to do that, because I personally prefer to keep the number of meds I take as few as possible. Sometimes various meds will counteract or confuse other meds anyway, sometimes in ways we aren't even aware of or understand.

So in my mind at the very least one of your current drugs should be completely eliminated. Preferably two. Whichever two you think are helping you the least. Just off the top of my head, that would probably be Paxil and Traz. I hate Traz anyway. That's a very complicated drug that can really confuse things.

I would probably keep the 300mg Adrafinil on board. And if stopping the other drugs is not an option for you, then perhaps at least lower Paxil to 10mg or 20mg.

In any case, start the Amisulpride at 25mg for 3 or 4 days to feel it out, then go up to 50mg. You could go up to 75mg or 100mg after a couple weeks if you wanted to, though that isn't often needed. Anywhere in the 50mg to 100mg range is fine.

And then give it a few to weeks to see. I generally find Amisulpride's benefits most evident starting in about week 3.

I wouldn't try anything else or change anything else until after Amisulpride has been given a fair shot. We just don't want to cloud the picture by changing other variables at the same time we're trying Amisulpride. The hardest part of the whole deal will be lowering or eliminating some of the other drugs you are taking, if you go that route. Brace yourself for some bumps in the road. As long as you know they're coming, you can be strong and weather the storm, knowing it will be only temporary, if it happens.
John


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