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Re: For all you Provigil vs. adrafinil watchers; N=1

Posted by Rick on July 17, 2000, at 21:17:52

In reply to For all you Provigil vs. adrafinil watchers; N=1, posted by shellie on July 17, 2000, at 11:23:17

> Since my last trial of provigil wasn't pure (new generic of aderex added variable), I am trying provigil again. Day 1- 100mg. The only reason I am trying again is that my pdoc would prefer provigal over adrafinil with an MAOI. (And I love my pdodc). I'll keep you informed. I have already ordered Adrafinil. (which actually gives the provigil a better chance of working, if you can follow superstitious logic). My new med trials don't seem to last very long. Last trial was ritalin with Nardil (3 days)--no energizing, no anything, but I felt suicidal (probably from changing pills every couple of days), so goodbye to ritalin. Shellie

Shellie -

I got a kick out of your superstitious logic! Believe me, I can relate (on a hundred different levels, not specifically regarding meds).


After I first talked with my pdoc about taking a stimulating med, I ended up with Wellbutrin, which brought back much of my anxiety even at a pretty small dose. He then wanted me to try Ritalin. But he FINALLY caved to my desire to try Provigil when I used persistence, research/anecdotal reports and threats (just joking on that last one...kind of) to talk him into letting me be his Provigil guinea pig instead. I'm sure glad I did! I know Ritalin has helped millions so very much, but it struck me as having lots more potential downside, especially as part of anxiety treatment. Heck, just the fact that he could simply phone in new prescriptions or refills for Provigil was appealing.

I think another thing that swayed my pdoc (who is a big Ritalin fan) is that, the very same day I brought up Provigil, he received a notice from Caremark (a prescription benefits company) practically begging doctors to prescribe Provigil for narcolepsy instead of the more traditional stimulants. He was floored, saying he had never seen anything like that before. He said, "it must be cheap", and then was double-floored when I informed him that, to the contrary it's an extremely pricey med.

But seeing all of the things (besides AD's) people have taken in tandem with Provigil, I wonder if I'm the only one who's ever taken it with a benzo (Klonopin). While Scott cited some interesting research suggesting that Provigil may work at cross-purposes to benzos by inhibiting GABA, it sure seems to be a nice, complementary combo for me. It feels like I'm mentally calm but at the same time cognitively stimulated and wide awake (when I want to be). Of course, for those who have a paradoxical fatigue reaction to Provigil (WITHOUT a possibly confounding factor like the generic aderex), it seems unlikely that Provigil could prove stimulating in the presence of a benzo. You know the old refrain..."Everbody Reacts Differently"

Anyways, has anyone besides me taken Provigil in tandem with a maintenance benzo? Results?

Thanks,
"N=1" (aka Rick...or were you referring to someone else?...don't worry, I won't be insulted!)


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