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Re: Short trials and moclobemide, Fred Potter

Posted by JohnL on May 4, 2000, at 0:53:39

In reply to Short trials and moclobemide, posted by FredPotter on May 3, 2000, at 15:35:23

> I took Moclobemide when I was very ill and it started to work on day 2 and definitely worked by day 3. The right drug for me therefore? Not so. It gradually flattened and dipped and my dose was put up finally to 600mg and I proceeded to get worse and worse until they changed it for Paxil, which did nothing for about 3 weeks. I had one day of feeling great and then the poop-out started. Let's face it, if short trials were a good indicator, we'd all be on alcohol or heroin.
> Fred

The phenomenon you mention--quick response which then fades or worsens--is a clue indicative of instable chemistry or instable electricity. This phenomenon is clearly identified and discussed in a book I was reading. Not just a case of chemical imbalance. And this of course warrants a whole new approach in drug selection priorities.


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