Posted by dom on March 19, 2000, at 21:44:29
In reply to Re: Mazindol (Mazinor) for depression? Anyone?, posted by saint james on March 19, 2000, at 0:05:00
> > Mazindol (Mazinor) is drug that is a potent reuptake inhibitor of both norepinephrine (NE) and dopamine (DA). Its primary indication is for the management of obesity. Infrequently, it has been used to treat depression.
> >
> > Has anyone ever tried mazindol for depression?
> >
> > Thanks.
>
>
> james here....
>
> I am weary of all weight loss meds. They seem to be too potent in their reuptake. Redux and another non-amphetamine wieght loss med have been shown to cause the same changes that MDMA causes. Too much of a good thing.
>
> In terms of weight loss, we know diet pills don't work. I've been on Dexadrine for years, one quickly gets used to the supression of appetite and if you continue to up the dose you will soon be called a speed freak. IF you suppress the appeitite you get rebound at nite and eat everything in the house. The higher the dose the more you eat. You cannot avoid this as you cannot stay on diet pills 24/7 and still be sane. On my normal dose of dex I have a normal appitite.
>
> The problem with all stims is that at some point
> they will deplete your body of neurotransmitters(NT's).While AD's hold or delay the deactivation of NT's, stims make more NT's available and at some point the well runs dry.
>
> To me the safest route is to go with the stims that have been out the longest, i.e. amphetamine (Dexadrine, Adderal, ect) Amphetamine has been with us since the 1920's. Taken at correct doses it is a very safe med, no flipper kids, ect. Very effective AD for some people. Amphetamine and AD's potentiate each other, often meaning you can take less of each. Try lower doses than used in ADD; start with 5 mgs/day in a slow release formulation like Dexadrine Spansule or Adderal; Dex being the cheaper. I feel it is best to start with stims + an AD; in myself if I take dex alone I do fine for a while but then get depressed.
>
> However, i have no ideas to offer in getting a doc to try any of this for depression w/o ADD.
> Most will not even think about it until all AD's and combos are tried.
>
> james
In my experience, the combination of Stimulents and Wellbutrin continues its anorectic effects indefinitely.
poster:dom
thread:27486
URL: http://www.dr-bob.org/babble/20000312/msgs/27603.html