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Reducing Prozac dosage

Posted by Dan on March 3, 2000, at 12:06:29

In the new edition of David Burns' "Feeling Good," he states that after several weeks of regular doses of Prozac (at which time it has reached a "steady state" blood level), it is possible to reduce the dosage dramatically--to 5 mg or less per day--without losing the antidepressive effect. Because of Prozac's long half-life, it only takes a little to replace the amount being lost. The advantage of reducing the dosage, he says, is that you can reduce or eliminate the side effects.

This is a very attractive idea for me, because after 7 weeks at 20 mg, I continue to have a whole range of fairly unpleasant side effects, although my mood has improved. I haven't seen any other sources making this claim, even though Burns says that it's "well known among the psychiatric profession." I saw some references to weekly dosing (20+ mg) in the Psychopharmacology Tips, but it seems to me that that might produce side effects for at least a short time after taking the Prozac.

Does anyone have any personal experience or other info about this kind of reduction? If so, how quickly could it be done, and how low could an efficacious dose be?

Thanks -
Dan


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poster:Dan thread:25790
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