Posted by Sam on February 16, 2000, at 23:37:58
In reply to Re: schizophrenic refractory pts. treatment, posted by Cam W. on February 9, 2000, at 23:05:07
> > Has anyone experienced a schizophrenic patient so refractory to treatment that you want to throw your arms up in the air and give up?
> > We have a schizophrenic pt,that has gone thu several ECT treatments , and is currently on Zyprexa 40mg and Clozapine treatment.
> > Nothing seems to touch this patient.
> > Any suggestions????
>
> Danielson - This probably won't help either, but some psychiatrists have said that adding low dose loxapine (5-50mg) can help. Loxapine acts as an atypical at these doses. Don't know if it will help, but may not hurt. I have never seen it added to that combination, but have seen some success in treatment-resistant cases using loxapine with the Zyprexa. By the way, as a caveat, I just heard Herbert Meltzer, the clozapine guru, talk on antipsychotic polypharmacy and he says that adding a traditional to an atypical or even combining two atypicals may saturate D2 too much leading to ESP.
> Sorry I cannot offer anymore. Good Luck - Cam W.How about a gram of Thorazine or 30-40mg Haldol?
poster:Sam
thread:20762
URL: http://www.dr-bob.org/babble/20000209/msgs/21914.html