Posted by Cindy W on February 10, 2000, at 20:44:16
In reply to Prozac vs. Serzone--some random comments, posted by jd on February 10, 2000, at 19:25:44
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> It's hard to say exactly why one med works
> and another doesn't. This being said, I'll
> add a few things to the above thread:
>
> -- I've tried a lot of ADs, including Serzone.
> For me, Serzone had nothing resembling the
> effects I typically associate with NE-boosting
> meds (such as tricyclics, effexor,
> or mianserin). On the contrary, it did feel
> rather serotenergic. This is subjective data
> of course, but not entirely meaningless.
>
> --Many people on this board have hypothesized
> that bad reactions to Serzone might have
> something to do with one of its metabolites,
> MCPP. Especially when MCPP breakdown is
> blocked by coadministration of another med,
> this could explain the paradoxical anxiety
> and hostility some people feel while taking
> it. Personally, I've yet to hear
> of or read an anecdote about someone who's had
> *great* response to Serzone, though I guess
> such people are out there somewhere.
>
> --jd
> jd, I agree with you that the effects felt serotonergic, except that there were no sexual side effects! Also, I did feel I had a very good response to Serzone for depression and social anxiety...unfortunately, it just doesn't decrease OCD or I'll still be taking it (I'm taking 40 mg/day of Serzone at night, and 300 mg of Effexor-XR in the daytime). I like Serzone!--Cindy W
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> > > In summary though I believe pretty strongly that how any drug works, or doesn't work, for a particular person is determined by many different factors at a molecular level involving the unique chemistry of that person. So to me the fact that literature seems to be in confusion of Serzone NE reuptake, it is nearly irrelevant as I see it. All that matters is that during a personal trial it either works or doesn't work. I wish I could understand all the whys and hows. I don't think I ever will. I'd be happy just to get well. JohnL
> >
> > Bull's-eye.
> >
> > > I'd be happy just to get well.
> >
> > I just wanted to see this written one more time.
> >
> > I would gladly give up all my psychopharm knowledge (of questionable quality and value) for mental health.
> >
> >
> > - Scott
> >
> >
> > An enthusiastic teen-age daughter of a New York Yankees VIP was given the opportunity to visit the team locker-room before a game. Being a big fan of Yogi Berra, she walked up to him and said, "Mr. Berra, I think you're the coolest." To that, Yogi replied, "Thank-you. You're not so hot yourself."
poster:Cindy W
thread:20849
URL: http://www.dr-bob.org/babble/20000209/msgs/21068.html