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Re: Zyprexa

Posted by Scott L. Schofield on December 31, 1999, at 15:36:14

In reply to Re: Zyprexa, posted by JohnL on December 31, 1999, at 3:03:21

> > My mother has been on Zyprexa for about 45 days and seems to have lost her ability to enunciate her words. I was just wondering if anyone else has experienced the same symptoms and if the inability to enunciate words is a side effect of Zyprexa.

> On a brief trial of Zyprexa I had perplexing speech and cognitive dysfunction. In addition, while driving I often blanked out and had no idea where I was, where I was going, or where I had been.

I experienced exactly the same things while taking Lamitcal at dosages exceeding 300mg/day. The driving thing is weird and scary. I guess the speech thing is dysphasia, which I believe is listed as a side-effect of Lamictal.

> A friend of mine takes Zyprexa. After my frightening experience with it, I noticed her slow speech, her difficulty putting words together, and her blanking out in the middle of sentences. I'm sure it doesn't affect everyone this way. But I can tell you in these two cases it did indeed cause marked speech and cognitive dysfunction. JohnL

I think these sorts of things are not uncommon among the psychotropics and anticonvulsants. But they usually donít appear until higher dosages are reached, or early in therapy, whereafter the side-effects can dissipate. From the postings Iíve read, it seems that the mood-stabilizing anticonvulsants are more apt to cause these cognitive changes than are antidepressants.

- Scott




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