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Re: 5-HTP lowers dopamine and norepinephrine

Posted by Scott L. Schofield on December 30, 1999, at 20:47:10

In reply to 5-HTP lowers dopamine and norepinephrine, posted by andrewb on December 21, 1999, at 14:10:51

> Here is a quote out of a book I read recently;
> In the early 1970s, Herman van Praag, M.D., and colleagues discovered that about one out of five patients who responded well to 5-HTP tended to relapse after one month of treatment. The antidepressant effects of 5-HTP in these subjects began to wear off gradually after the first month despite the fact that the level of 5-HTP in their blood, and presumably the level of serotonin in the brain, remained at the same level as when they were experiencing a benefit.

In the early to mid 80s, some studies were conducted involving tryptophan-depletion. Patients who were taking non-SSRI antidepressants and who were in remission were fed a diet of food lacking tryptophan (the precursor of 5-HTP; 5-HTP being the precursor of serotonin). While continuing with their antidepressants, a number of these people became depressed again. When tryptophan was added back into their diets, their depressions lifted.

- Scott




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