Psycho-Babble Medication | about biological treatments | Framed
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Re: to Scott

Posted by andrewb on December 29, 1999, at 12:01:19

In reply to Re: New Offshore Supplier! Mirapex available!, posted by Scott L. Schofield on December 28, 1999, at 9:50:21


Thank you for your very interesting posting. To answer your question, the generic name for Mirapex is pramipexole and the generic for Requip is ropinirole. Both are non-ergot D2 receptor agonists that act on the striatum.
I have recently had what seems like a partial poop out on amisulpride after 4 months of effectiveness. That is less energy, more daytime sleepiness and less motivation. Another person wrote that she experienced poop out after an initial robust response to Mirapex. It occurs to me that maybe we aren't experiencing poop out after all, rather I may be taking too much amisulpride and she too little Mirapex. I am taking 100 mgs/day of amisulpride though studies have shown 50 mgs./day to be just as effective. Any ideas here. What would happen if a dopamine agonist like Mirapex was combined with Amisulpride. Could this possibly be an more effective antidepressant cocktail. I also was wondering what the difference was between ropinirole and pramipexole. Perhaps the only difference is the relative degree of binding affinity to the D2 (and D3?) receptors but to the patient pretty much the same effect is experienced.
Thanks for any info.,





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