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Re: Lithium and Glutamate, Professional expertise?

Posted by Abby on December 22, 1999, at 0:05:44

In reply to Re: Meaning of the word serotenergic?, posted by Noa on December 21, 1999, at 21:16:15

> Good questions. A lot of the neurochemistry is above my science capacities. I probably could learn to understand it better, but would need someone to teach me some basics.
> Ok, that being said, can I ask more about lithium? Am I way off if I remember hearing that lithium affects glutemate, which is somehow connected to the breakdown of serotonin that is not taken up? Or did I dream this in my wierd and vivid AD dreams?

Lithium does 'stabilize' glutamate which seem
to affect the speed at which information is passed
between neurons. Crudely, too much and your manic,
too little and you're slowed down perhaps to a
depressive state. That much I know, but lithium
is described as serotenergic and I believe
dopaminergic, but nobody has explained ( at least to me)what this
means or how glutamate would affect this.





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