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Why does Nardil help social phobia?

Posted by DC on December 11, 1999, at 6:49:13

In reply to social anxiety-HELP!!!, posted by Mark on November 27, 1999, at 1:47:01

I'm wondering if anyone knows what neurochemical effects MAOI's have and which of these is the most likely reason they are effective. I know Nardil inhibits MAO and that this effects levels of serotonin and dopamine and I know it has some effect on GABA levels. Seems like Nardil is a rather "dirty" drug, unlike say Prozac which pretty much just works on Serotonin. Since Nardil works on all these different neurochemicals, it's hard to know what exactly is responsible for its effectiveness. Or perhaps the good result comes from the synergy of these different effects.

Does Nardil work on Gaba the same way Benzos do? Or does it operate more like some of the anticonvulsants like Depakote, Neurontin, etc. The reason I'm wondering is because I've heard that a new drug called pregabalin might be effective for social phobia.




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