Psycho-Babble Medication | about biological treatments | Framed
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Re: would you believe 250mg?

Posted by Elizabeth on December 4, 1999, at 9:14:43

In reply to would you believe 250mg?, posted by george o on December 1, 1999, at 1:22:55

> i developed rapid tolerance to parnate and had to have it increarsed every week or two until we got over 200mg, my doctor did this after consulting with an expert at his school (he was a resident). the horrible thing was that there seemed to be a rebound effect, where not only did my depression return as i developed tolerance but i became twice as depressed as i had been to start.

This happened to me with Nardil. Increasing the dose didn't seem to help much but I wasn't as aggressive about it as you seem to have been.

There's a handful of cases reported in the literature of Parnate "addiction;" I wonder if many or most of these weren't actually just plain old tolerance, as you describe.




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