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counteracting reboxetine's anticholinergic FX

Posted by Erik Hanson on December 4, 1999, at 8:03:10

Hi all. The anticholinergic side effects of reboxetine
do seem to be the problem--they are the reason I stopped
taking it (from Edronax) after an otherwise adequate
trial. Does anyone know if high dose nicotine (trans-
dermal or other non-tobacco source) or DMAE or choline
could counteract the anticholinergic effects? Why is
it that there isn't some strategy out there to reverse
the anticholinergic effects? Does anyone know specifically
which muscarinic receptor subtypes reboxetine binds to?
Maybe this info. isn't in the literature yet.

Erik H.




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