Psycho-Babble Medication | about biological treatments | Framed
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I like the idea of SSRI or NARI augmentation

Posted by JohnB on November 19, 1999, at 8:26:34

In reply to Re: Think twice Dee!, posted by CraigF on November 18, 1999, at 18:25:59

Hi. The notion of SSRI or SNRI augmentation with Pindolol has demonstrated efficacy. SSRI and SNRI augmentation with Buspar also has demonstrated efficacy. Pindolol, as a postsynaptic and presynaptic 5HT1A antagonist has demonstrated ability to shorten the time of onset of action of SSRI's, SNRI's, and MAOI's. Buspar, a presynaptic and postsynaptic 5HT1A partial agonist can only be combined with SSRI's and SNRI's, not MAOI's. Being psychdocs prescribed to improve cognitive function, frequently an issue with ANY CNS depressant.

So, keep the two effects separate, as you discuss with your psychiatrist, who should be a psychopharmacologist. Pindolol will most likely increase onset of therapeutic action. Buspar may minimize cognitive side effects as well as help with sexual dysfunction, if that is an issue.

As far as contraindications, take that somewhat with a grain of salt. Many experienced pscyhopharmacologists will carefully manage drug combinations which are contraindicated, such as Bupropion and MAOI's.

Definitely, never self-medicate. Discuss with your psychdoc all medications you're taking, whether synthetic pharmaceuticals, or alternative OTC medications.





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